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Maximizing Lion's Mane Benefits: Powerful Bioactives from Entire Fruiting bodies & mycelium

Updated: Apr 3

Mushroom supplements, particularly Lion's Mane extract, have garnered attention for their potential health benefits recently. However, with the abundance of conflicting information in the market, it is crucial to delve into the source of these supplements to make informed choices. In researching the benefits of functional mushrooms, you've probably come across the "mycelium vs. fruiting body" debate. You likely have questions such as: Is one more beneficial than the other? Our focus here is on comparing the advantages of using Lion's Mane extract derived from both Fruiting bodies and Mycelium.

We at GREENDORSE, prepare Full Spectrum Lion's Mane Mushroom Extracts from properly harvested Fruiting bodies & added Erinacines from Mycelium. The fruiting body of the good premium quality Lion's Mane Mushroom usually has a Beta-Glucan content of 30% or more. The mycelium, on the other hand, has a beta-glucan content of only around 5%, sometimes falling as low as zero. Many supplements in the market use only mycelium-based extracts because they are more economical to produce. The fruiting body of the Lion's Mane mushroom is packed with a higher concentration of full-spectrum bioactive compounds, including polysaccharides, beta-glucans, hericenones, etc which are crucial for the mushroom's neuroprotective & cognitive-enhancing benefits. While mycelium is rich in another Neuroprotective active compound named Erinacines. If you want a mushroom product that’s biologically full spectrum active with beta-glucans and both active compounds hericenones and erinacines, then look for this one. Ideally, a great Lion's mane supplement should be made from both fruiting bodies and mycelium to reap all the health benefits of Lion's mane.

This distinction is very important because scientific studies recently have shown that to get full spectrum benefits, Lion's mane mycelium is as important as the fruiting body. In Lion’s Mane mycelium, you find erinacines which are not found in the fruit bodies at all. So far there is no research indicating the presence of functional erinacines in fruiting bodies. Erinacines can cross the blood-brain barrier and are the most suitable compound in Lion’s Mane with “confirmed pharmacological action on the nervous system”. They have been shown in animals to increase the Nerve Growth Factor (NGF) and Brain Derived Neurotrophic Factor (BDNF) which are both important in maintaining neuronal function. Erinacines from Mycelium and Hericenones from fruiting bodies therefore likely behind much of the neuroprotective/enhancing effect of Lion’s Mane supplements.

Research Studies say:

  • Mycelium: Erinacines are the stars, known for stimulating nerve growth.

  • Fruits: Hericenones take the trophy for boosting nerve growth factor (NGF).

Hot Take: Want to get brainy? Choose fruits for hericenones but don’t underestimate mycelium’s erinacines as it is the one able to cross blood-brain barriers. Hence, our products must contain a source of both hericenones & erinacines. Therefore a combination of both fruiting bodies and mycelium is used in GREEDNDORSE Lion's Mane Mushroom Extract.

Overall, the main key points about our Lion's mane extract are given below:

1. Rich in Beta-glucans: The fruiting bodies of Lion's Mane mushrooms are rich in polysaccharides such as Beta-glucans. They promote the growth of beneficial gut bacteria, bolstering the immune system and enhancing brain health. Our Lion's Mane Extract offers almost 34% Beta-glucans, maximizing these benefits.

2.  Full Spectrum Extract with Active Compounds: The Lion's Mane fruiting body contains a higher concentration of active compounds such as hericenones associated with neuroprotection and nootropic effects. As it contains more than 30% Beta-glucans already this indicates premium quality real mushroom extract made with rich fruiting bodies as well as rich in other functions bioactive compounds. Besides, this also includes mycelium as well in the extraction method to give the required content of erinacines as well.

3.  Dual extraction method & 3rd Party Lab Report: A double extraction method is used for this extract as we aim to get as many bioactive compounds as we can get, using both a water solvent and an alcohol solvent. Our extract is standardized for beta-glucans content hence extraction is done first with a hot water extraction method with a temperature ranging from 75 - 85 degrees Celsius. Water being polar dissolves all polar molecules, including most beta-glucans. After that, an ethanol extraction method is used to extract non-polar molecules quickly that are left behind in a water extraction step. This includes triterpenoids and other lipid-based molecules. Since hericenones and erinacines are fat-soluble diterpenoids, the ethanol extraction method is very important to obtain them.

4. Third Party Lab Report: Our product is reported by a 3rd party NABL and FSSAI accredited lab for its greater than 30% Beta-glucans content using Megazyme Enzymatic Kit. Megazyme's β-Glucan Enzymatic Kit (K-YBGL) is used for the specific measurement and analysis of 1,3:1.6-β-Glucan, 1,3-β-glucan from other fibers and 1,4:1,6-α-glucans (starch). Many use AOAC.911.43 method to quantify β-glucan in the mushroom extracts they are selling, & showing the same in their reports. We want to strictly emphasize that AOAC.911.43 is not a specific method to measure β-glucan in mushrooms, it is used to analyze total dietary fibers (DF) in food, both soluble DF & Insoluble DF.

Research-backed Benefits of Lion's Mane Extract:

Lion's Mane extract has been the subject of numerous research studies, uncovering a multitude of health benefits associated with its consumption. Let's explore some of the key findings that support the use of this incredible natural extract.


1. Enhanced Brain Function: The hericenones and erinacines found in Lion's Mane extract have been shown to increase NGF production, which is essential for the growth and maintenance of nerve cells. By stimulating NGF production, Lion's Mane extract has the potential to improve cognitive function, enhance memory, and support overall brain health.


2. Neuroprotective Effects: Several studies have demonstrated the neuroprotective properties of Lion's Mane extract. It has been shown to help reduce symptoms of neurological conditions such as Alzheimer's and Parkinson's diseases. This natural extract may help protect nerve cells from damage and potentially slow down the progression of these disorders.


3. Mood and Mental Well-being: Lion's Mane extract has been found to have potential mood-boosting effects. In one study, participants who consumed Lion's Mane extract reported improved feelings of calmness and reduced anxiety. This suggests that Lion's Mane extract may have a positive impact on mental well-being and stress management.


4. Immune System Support: The beta-glucans present in Lion's Mane extract have been found to modulate the immune system, helping to enhance its response against infections and illnesses. Research has shown that Lion's Mane extract can stimulate the activity of immune cells, improving overall immune function.

How to Choose a Quality Lion's Mane Extract Product:

When it comes to choosing a quality Lion's Mane extract product, there are a few key factors to consider. First and foremost, it's important to look for a product that is made from a combination of fruit bodies and mycelium. This combination ensures that you are getting a comprehensive range of beneficial compounds found in Lion's Mane.


Secondly, look for products that are third-party tested for purity and potency. This will ensure that you are getting a reliable and effective product that meets the highest quality standards.


Lastly, consider the extraction method used. Look for products that utilize advanced extraction methods, such as hot water extraction or dual extraction, to maximize the bioavailability of the active compounds in Lion's Mane.


By considering these factors, you can ensure that you are getting the most out of your Lion's Mane extract and maximizing its health benefits. In the next section, we will explore some dosages and ways to incorporate Lion's Mane extract into your daily routine. Stay tuned for more valuable information on maximizing the power of Lion's Mane extract.

Maximizing Health Benefits: Best Practices and Recommendations


Now that we have discussed the potential of Lion's Mane extract, let's delve into how you can maximize its health benefits and incorporate it into your daily routine.


1. Quality Matters: When purchasing Lion's Mane extract, it is crucial to choose a reputable brand that guarantees the highest quality. Look for products that are third-party tested for purity, potency, and contaminants.


2. Dosage and Frequency: The recommended dosage of Lion's Mane extract varies depending on the individual and the specific brand. Start with the lowest effective dose and gradually increase as tolerated. It is advisable to follow the manufacturer's instructions or consult with a healthcare professional to determine the appropriate dosage and frequency for your needs.


3. Consistency is Key: To experience the full benefits of Lion's Mane extract, it is important to incorporate it into your routine consistently. Regular consumption over time is more likely to yield positive results than sporadic use.


4. Combine with a Healthy Lifestyle: While Lion's Mane extract can provide numerous health benefits, it is important to remember that it is not a miracle solution. To maximize the potential benefits, it should be paired with a balanced diet, regular exercise, adequate sleep, and stress management.

5. Monitor and Listen to Your Body: Pay attention to how your body responds to Lion's Mane extract. Everyone's physiology is unique, and what may work for one person might not work for another. If you experience any adverse effects or do not notice any positive changes after a reasonable trial period, it may be worth consulting with a healthcare professional to reassess your approach.


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